HitPredict

Interactor 1: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Interactor 2: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	35938192, 37102239
Identification Methods	enzymatic study, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 152
+	Mm
		1145473 H2B2B_MOUSE (1-126): 2.99e-55: 170: 96.03		UBE2A_MOUSE (1-152): 3.88e-76: 225: 100.00
+	Hs
		829009 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBE2A_HUMAN (1-152): 3.88e-76: 225: 100.00
+	Hs
		828971 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		UBE2A_HUMAN (1-152): 3.88e-76: 225: 100.00
+	Hs
		828968 H2B1D_HUMAN (1-126): 2.89e-54: 167: 97.62		UBE2A_HUMAN (1-152): 3.88e-76: 225: 100.00
+	Mm
		927791 H2B2B_MOUSE (1-126): 2.99e-55: 170: 96.03		UBE2B_MOUSE (1-151): 3.28e-74: 219: 96.03
+	Hs
		927767 H2B1A_HUMAN (1-126): 8.03e-47: 148: 85.83		UBE2B_HUMAN (1-151): 3.28e-74: 219: 96.03
+	Sc
		355730 H2B2_YEAST (3-125): 1.47e-40: 133: 70.73		UBC2_YEAST (1-150): 2.29e-73: 218: 69.33
+	Sc
		355294 H2B1_YEAST (3-125): 4.34e-36: 121: 70.73		UBC2_YEAST (1-150): 2.29e-73: 218: 69.33