HitPredict

Interactor 1: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Interactor 2: UBP48 (Q86UV5)
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48)
Gene: USP48

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27248496, 33903120
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1035
+	Hs
		420851 H2B1J_HUMAN (1-126): 8.38e-55: 169: 97.62		UBP48_HUMAN (1-1035): 0: 1274: 100.00
+	Hs
		918483 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		UBP48_HUMAN (1-1035): 0: 1274: 100.00
+	Mm
		500577 H2B1F_MOUSE (1-126): 1.08e-53: 166: 96.83		UBP48_MOUSE (1-1035): 0: 1245: 92.03
+	Hs
		420891 H2B1J_HUMAN (1-126): 8.38e-55: 169: 97.62		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Hs
		241654 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Hs
		707772 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP36_HUMAN (15-525): 2.42e-103: 351: 18.10
+	Dm
		355274 H2B_DROME (36-126): 1.48e-46: 148: 95.60		UBP7_DROME (81-487): 9.74e-110: 369: 26.28
+	Hs
		1087318 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		707705 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		1231220 H2B3B_HUMAN (1-126): 2.37e-52: 163: 96.03		UBP7_HUMAN (66-487): 5.02e-100: 341: 26.05
+	Hs
		259286 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP12_HUMAN (54-422): 1.09e-100: 323: 22.42
+	Hs
		905383 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP46_HUMAN (54-421): 7.22e-101: 323: 22.73
+	Hs
		905394 H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83		UBP46_HUMAN (54-421): 7.22e-101: 323: 22.73
+	Hs
		1087411 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP42_HUMAN (45-435): 1.3e-91: 321: 20.40
+	Hs
		271037 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP2_HUMAN (38-425): 1.46e-95: 317: 20.98
+	Hs
		707807 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP3_HUMAN (12-430): 3.93e-96: 316: 19.38
+	Hs
		918801 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		UBP3_HUMAN (12-430): 3.93e-96: 316: 19.38
+	Hs
		1087489 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP22_HUMAN (16-400): 5.16e-95: 313: 19.38
+	Hs
		707794 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP22_HUMAN (16-400): 5.16e-95: 313: 19.38
+	Hs
		1087499 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP20_HUMAN (21-199): 3.28e-29: 128: 17.44