HitPredict

Interactor 1: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Interactor 2: TSYL1 (Q9H0U9)
Testis-specific Y-encoded-like protein 1 (TSPY-like protein 1)
Gene: TSPYL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 437
+	Hs
		707676 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		TSYL5_HUMAN (30-436): 3.68e-135: 396: 37.68
+	Hs
		1329387 U3KQK0_HUMAN (1-126): 2.3e-56: 174: 98.41		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		1307095 H2B1N_HUMAN (1-126): 2.99e-54: 167: 98.41		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		965383 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		TSPY1_HUMAN (135-429): 6.88e-94: 287: 37.29
+	Hs
		886086 H2B1D_HUMAN (1-126): 2.89e-54: 167: 97.62		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Rn
		961590 H2B1_RAT (1-126): 8.26e-52: 161: 94.44		TSPY1_RAT (101-408): 1.53e-86: 269: 34.69
+	Hs
		963873 H2B1A_HUMAN (1-126): 8.03e-47: 148: 85.83		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Hs
		1087365 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		420873 H2B1J_HUMAN (1-126): 8.38e-55: 169: 97.62		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		707727 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		1231232 H2B3B_HUMAN (1-126): 2.37e-52: 163: 96.03		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		876805 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		707565 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		876745 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		876845 H2B3B_HUMAN (1-126): 2.37e-52: 163: 96.03		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		1282951 H2B1A_HUMAN (1-126): 8.03e-47: 148: 85.83		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		876869 H2B1A_HUMAN (1-126): 8.03e-47: 148: 85.83		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Dm
		355262 H2B_DROME (36-126): 1.48e-46: 148: 95.60		Q24150_DROME (173-408): 1.4e-64: 213: 18.07
+	Dm
		355275 H2B_DROME (36-126): 1.48e-46: 148: 95.60		Q9W1G7_DROME (173-408): 1.39e-64: 213: 18.07