HitPredict

Interactor 1: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Interactor 2: UBP16 (Q9Y5T5)
Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-processing protease UBP-M) (Ubiquitin-specific-processing protease 16)
Gene: USP16

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	24013421
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 823
+	Hs
		241667 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		UBP16_HUMAN (1-823): 0: 628: 100.00
+	Hs
		918798 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		UBP16_HUMAN (1-823): 0: 628: 100.00
+	Hs
		1307158 H2B1L_HUMAN (1-126): 3.02e-53: 164: 96.03		UBP16_HUMAN (1-823): 0: 628: 100.00
+	Hs
		1129817 H2B2F_HUMAN (1-126): 2.99e-55: 170: 96.03		UBP45_HUMAN (3-823): 2.47e-153: 470: 37.06
+	Hs
		1174153 H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83		UBP45_HUMAN (3-823): 2.47e-153: 470: 37.06
+	Hs
		1087499 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP20_HUMAN (17-821): 3.01e-112: 365: 18.72
+	Hs
		707666 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP43_HUMAN (169-821): 4.75e-98: 331: 16.79
+	Hs
		707665 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP51_HUMAN (465-821): 3.12e-48: 184: 20.38
+	Hs
		1087489 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP22_HUMAN (454-823): 6.46e-48: 180: 19.42
+	Hs
		707794 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP22_HUMAN (454-823): 6.46e-48: 180: 19.42
+	Hs
		271037 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP2_HUMAN (629-820): 1.25e-39: 157: 26.94
+	Hs
		707807 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		UBP3_HUMAN (527-819): 1.63e-37: 149: 22.19
+	Hs
		918801 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		UBP3_HUMAN (527-819): 1.63e-37: 149: 22.19
+	Hs
		1087213 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP49_HUMAN (611-821): 5.62e-16: 84.3: 30.84
+	Hs
		1087506 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		UBP15_HUMAN (388-558): 4.48e-10: 65.5: 7.47
+	Sc
		355943 H2B2_YEAST (3-125): 1.47e-40: 133: 70.73		UBP8_YEAST (629-819): 7.6e-18: 89.4: 33.16
+	Sc
		355547 H2B1_YEAST (3-125): 4.34e-36: 121: 70.73		UBP8_YEAST (629-819): 7.6e-18: 89.4: 33.16