HitPredict

Interactor 1: WIS1 (P33886)
Protein kinase wis1 (EC 2.7.12.2) (Protein kinase sty2)
Gene: WIS1

Interactor 2: HOG1 (Q09892)
Mitogen-activated protein kinase sty1 (MAP kinase sty1) (EC 2.7.11.24) (MAP kinase spc1)
Gene: sty1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.964

The method score is based on:

Property Details
Experiments 12181336, 9718372, 10398679, 7501024, 26432170, 26771498, 9585506, 23695164
Identification Methods affinity chromatography technology, enzymatic study, two hybrid, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 605
Sp

1 349
+ Sc
+ At
+ Hs
+ At
+ At
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ At
+ Rn
+ At
+ At
+ Hs
+ Hs
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024