HitPredict

Interactor 1: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Interactor 2: RBG2 (P53295)
Ribosome-interacting GTPase 2 (GTP-binding protein RBG2)
Gene: RBG2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.50	0.626

Property	Details
Experiments	23899355, 18467557, 21076151, 16429126
Identification Methods	affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2672 Sc			1 368
+	Sc
		707863 GCN1_YEAST (1-2672): 0: 1798: 100.00		RBG1_YEAST (2-368): 5.55e-126: 368: 50.95
+	Sc
		707843 GCN1_YEAST (1-2672): 0: 1798: 100.00		OLA1_YEAST (45-365): 1.96e-77: 245: 14.87
+	Sc
		707914 GCN1_YEAST (1-2672): 0: 1798: 100.00		NOG1_YEAST (24-281): 1.22e-53: 189: 18.05
+	Sc
		561034 EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87		RBG2_YEAST (1-368): 5.53e-130: 378: 100.00
+	Sc
		560959 EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87		OLA1_YEAST (45-365): 1.96e-77: 245: 14.87
+	Sc
		560968 EF3A_YEAST (1321-1710): 6.99e-83: 299: 22.87		YLF2_YEAST (51-362): 7.34e-63: 207: 16.96
+	Sc
		746611 NEW1_YEAST (1361-1636): 7.06e-35: 149: 18.95		OLA1_YEAST (45-365): 1.96e-77: 245: 14.87
+	Sp
		144034 2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92		OLA1_SCHPO (45-364): 8.66e-73: 233: 13.37
+	Hs
		1202100 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		GTPB4_HUMAN (24-313): 1.65e-64: 218: 18.63
+	Hs
		59610 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		GTPBA_HUMAN (28-185): 2.19e-45: 161: 28.89