HitPredict

Interactor 1: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Interactor 2: CDC14 (Q00684)
Tyrosine-protein phosphatase CDC14 (EC 3.1.3.48)
Gene: CDC14

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21127052
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2672 Sc			1 551
+	Sp
		1013477 GCN1_SCHPO (13-2665): 0: 1248: 32.29		FLP1_SCHPO (3-548): 4.89e-156: 458: 40.00
+	Hs
		1167728 GCN1_HUMAN (1-2622): 0: 1449: 25.42		TPTE2_HUMAN (149-341): 7.84e-47: 173: 20.59
+	Hs
		879832 GCN1_HUMAN (1-2622): 0: 1449: 25.42		TPTE_HUMAN (149-341): 6.43e-45: 168: 19.61
+	Hs
		260591 GCN1_HUMAN (1-2622): 0: 1449: 25.42		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		1260263 GCN1_HUMAN (1-2622): 0: 1449: 25.42		PTPM1_HUMAN (189-326): 2.73e-31: 121: 23.65
+	Sc
		866890 EF3B_YEAST (1321-1674): 3.58e-82: 297: 22.69		CDC14_YEAST (1-551): 0: 564: 100.00
+	Sp
		1350777 2AAA_SCHPO (1640-2239): 9.32e-33: 138: 12.92		FLP1_SCHPO (3-548): 4.89e-156: 458: 40.00
+	Hs
		253731 2AAA_HUMAN (1315-1936): 3.9e-70: 250: 14.42		AUXI_HUMAN (145-389): 9.52e-40: 156: 14.73
+	Hs
		56511 2AAA_HUMAN (1315-1936): 3.9e-70: 250: 14.42		PTPC1_HUMAN (162-371): 6.16e-37: 147: 18.06
+	Hs
		256760 CAND2_HUMAN (814-1829): 2.77e-48: 192: 11.31		TPTE2_HUMAN (149-341): 7.84e-47: 173: 20.59
+	Hs
		256741 CAND2_HUMAN (814-1829): 2.77e-48: 192: 11.31		TPTE_HUMAN (149-341): 6.43e-45: 168: 19.61
+	Hs
		56512 2AAB_HUMAN (1663-2209): 4.74e-57: 212: 14.98		PTPC1_HUMAN (162-371): 6.16e-37: 147: 18.06
+	Mm
		139429 CAND1_MOUSE (814-1469): 5.19e-10: 67.4: 13.69		PTEN_MOUSE (152-540): 4.63e-74: 242: 14.53
+	Hs
		890725 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Dm
		1181090 CAND1_DROME (808-2002): 4.48e-21: 104: 10.33		Q7KMQ6_DROME (152-540): 1.45e-42: 161: 13.98
+	Hs
		260568 ECM29_HUMAN (1400-2598): 3.58e-14: 81.2: 10.27		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		155496 TNPO2_HUMAN (2197-2581): 2.64e-10: 68.2: 12.16		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		1088019 CAND1_HUMAN (814-1469): 2.62e-09: 65.1: 13.54		DUS6_HUMAN (189-352): 2.78e-38: 146: 13.02
+	Hs
		1273211 TNPO1_HUMAN (2073-2625): 4.61e-13: 77.5: 11.45		DUS23_HUMAN (173-334): 4.6e-36: 133: 20.99
+	Hs
		1260266 TNPO1_HUMAN (2073-2625): 4.61e-13: 77.5: 11.45		PTPM1_HUMAN (189-326): 2.73e-31: 121: 23.65