HitPredict

Interactor 1: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Interactor 2: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 857 Hs			1 621
+	Hs
		843686 KPCD1_HUMAN (176-857): 3.37e-133: 421: 15.27		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Hs
		843891 KPCD2_HUMAN (140-855): 7.56e-120: 386: 14.74		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Mm
		1142065 PAK3_MOUSE (237-800): 1.6e-121: 380: 18.45		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Mm
		103570 G5E884_MOUSE (239-800): 9.68e-119: 372: 18.04		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Mm
		292042 PAK1_MOUSE (239-792): 1.16e-115: 364: 18.47		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Hs
		843969 KCC2A_HUMAN (525-856): 3.17e-95: 308: 22.13		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Hs
		844073 KPCD1_HUMAN (176-857): 3.37e-133: 421: 15.27		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Mm
		515232 KCC2A_MOUSE (525-856): 5.71e-95: 308: 21.84		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Hs
		844047 KCC2D_HUMAN (519-856): 1.32e-113: 357: 22.95		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Mm
		578255 KS6A1_MOUSE (477-790): 2.64e-67: 239: 20.77		FXR2_MOUSE (4-621): 0: 810: 56.12
+	Mm
		1143319 KPCD1_MOUSE (177-853): 1.09e-133: 423: 15.53		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		729495 KPCD1_MOUSE (177-853): 1.09e-133: 423: 15.53		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		1207051 PAK5_MOUSE (178-798): 1.92e-117: 374: 16.31		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		1161535 KCC2D_MOUSE (519-856): 1.32e-113: 357: 22.95		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		729551 PAK5_MOUSE (178-798): 1.92e-117: 374: 16.31		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		729519 KCC2D_MOUSE (519-856): 1.32e-113: 357: 22.95		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		515247 KCC2A_MOUSE (525-856): 5.71e-95: 308: 21.84		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		515218 KCC2A_MOUSE (525-856): 5.71e-95: 308: 21.84		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Hs
		989201 KCC2A_HUMAN (525-856): 3.17e-95: 308: 22.13		FMR1_HUMAN (1-506): 0: 599: 51.13