HitPredict

Interactor 1: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Interactor 2: C5AR2 (Q9P296)
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Gene: C5AR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 857 Hs			1 337
+	Hs
		598922 TTK_HUMAN (1-857): 0: 776: 100.00		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		708278 TTK_HUMAN (1-857): 0: 776: 100.00		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		708264 TTK_HUMAN (1-857): 0: 776: 100.00		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		708266 TTK_HUMAN (1-857): 0: 776: 100.00		OPRX_HUMAN (5-323): 1.76e-61: 202: 22.39
+	Hs
		666346 KPCD2_HUMAN (140-855): 7.56e-120: 386: 14.74		NK3R_HUMAN (1-335): 3.01e-63: 209: 16.90