Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: MCM8 (Q9UJA3)
DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8)
Gene: MCM8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12771218
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_OB, MCM~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016887 - ATP hydrolysis activity
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 863
Hs

1 840
+ Hs
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+ Xl
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+ Dm
+ Dm
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+ At
+ Xl
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+ Dm

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Last updated: 15 Jul 2024