HitPredict

Interactor 1: MCM4 (P33991)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)
Gene: MCM4

Interactor 2: ORC6 (Q9Y5N6)
Origin recognition complex subunit 6
Gene: ORC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	12614612, 15232106
Identification Methods	two hybrid, pull down, protein array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	MCM_lid~ORC6
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 863 Hs			1 252
+	Hs
		832807 MCM2_HUMAN (2-839): 0: 762: 27.95		ORC6_HUMAN (1-252): 7.09e-123: 351: 100.00
+	Hs
		708813 MCM5_HUMAN (133-846): 0: 698: 30.23		ORC6_HUMAN (1-252): 7.09e-123: 351: 100.00
+	Hs
		1055666 MCM6_HUMAN (138-842): 0: 675: 26.97		ORC6_HUMAN (1-252): 7.09e-123: 351: 100.00
+	Hs
		709134 MCM7_HUMAN (158-841): 0: 660: 29.88		ORC6_HUMAN (1-252): 7.09e-123: 351: 100.00