Interactor 1: EP300 (B2RWS6)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: F8VPR5 (F8VPR5)
histone acetyltransferase (EC 2.3.1.48)
Gene: Crebbp

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24586743
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~Bromodomain, Bromodomain~RING_CBP-p300, HAT_KAT11~HAT_KAT11, ZZ~ZZ
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000123 - histone acetyltransferase complex
GO:0001223 - transcription coactivator binding
GO:0002039 - p53 binding
GO:0003684 - damaged DNA binding
and 12 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2412
Mm

1 2441
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs
+ At
+ Hs
+ Dm
+ Mm
+ Hs
+ Zm
+ Hs
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024