HitPredict

Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: HIPK4 (Q8NE63)
Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)
Gene: HIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 719 Hs			1 616
+	Hs
		625168 MCM7_HUMAN (1-719): 0: 786: 100.00		CDK2_HUMAN (8-281): 8.05e-123: 366: 26.17
+	Hs
		708896 MCM7_HUMAN (1-719): 0: 786: 100.00		KCC2G_HUMAN (3-425): 3.45e-118: 364: 17.95
+	Hs
		708633 MCM5_HUMAN (6-716): 0: 682: 27.61		KCC2G_HUMAN (3-425): 3.45e-118: 364: 17.95
+	Hs
		708634 MCM5_HUMAN (6-716): 0: 682: 27.61		KCC2D_HUMAN (2-326): 8.49e-117: 358: 20.00
+	Rn
		92855 E9PTS4_RAT (6-716): 0: 661: 26.95		AAPK1_RAT (7-540): 3.74e-116: 359: 18.46
+	Hs
		625235 MCM2_HUMAN (8-690): 0: 643: 28.13		CDK2_HUMAN (8-281): 8.05e-123: 366: 26.17
+	Sc
		675511 MCM4_YEAST (7-703): 0: 658: 29.69		HOG1_YEAST (3-377): 8.57e-114: 348: 22.11
+	Hs
		625167 MCM4_HUMAN (5-700): 0: 636: 31.52		CDK2_HUMAN (8-281): 8.05e-123: 366: 26.17
+	Hs
		832416 MCM2_HUMAN (8-690): 0: 643: 28.13		AAPK1_HUMAN (7-540): 2.52e-115: 357: 18.13
+	Hs
		625435 MCM6_HUMAN (3-715): 0: 623: 28.05		CDK2_HUMAN (8-281): 8.05e-123: 366: 26.17
+	Hs
		414822 MCM2_HUMAN (8-690): 0: 643: 28.13		CDK1_HUMAN (8-349): 1.61e-111: 337: 22.67
+	Hs
		709127 MCM7_HUMAN (1-719): 0: 786: 100.00		DYR1B_HUMAN (11-360): 2.49e-52: 191: 37.68
+	Hs
		414780 MCM4_HUMAN (5-700): 0: 636: 31.52		CDK1_HUMAN (8-349): 1.61e-111: 337: 22.67
+	Dm
		247439 MCM4_DROME (5-714): 0: 624: 29.95		MK38B_DROME (3-401): 6.78e-112: 341: 22.63