HitPredict

Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: DAPLE (Q9P219)
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
Gene: CCDC88C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 719 Hs			1 2028
+	Hs
		708910 MCM7_HUMAN (1-719): 0: 786: 100.00		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		709034 MCM7_HUMAN (1-719): 0: 786: 100.00		CP250_HUMAN (613-1708): 8.43e-35: 149: 11.02
+	Hs
		148448 MCM7_HUMAN (1-719): 0: 786: 100.00		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		708696 MCM5_HUMAN (6-716): 0: 682: 27.61		HOOK3_HUMAN (4-548): 2.59e-25: 116: 24.56
+	Hs
		832468 MCM2_HUMAN (8-690): 0: 643: 28.13		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		148447 MCM5_HUMAN (6-716): 0: 682: 27.61		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		708443 MCM4_HUMAN (5-700): 0: 636: 31.52		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		708563 MCM5_HUMAN (6-716): 0: 682: 27.61		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		1055556 MCM6_HUMAN (3-715): 0: 623: 28.05		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		832772 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH2_HUMAN (1047-1739): 2.12e-27: 124: 10.21
+	Hs
		522541 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH1_HUMAN (1047-1739): 3.07e-26: 120: 9.93
+	Hs
		528364 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH6_HUMAN (942-1722): 7.95e-26: 119: 9.30
+	Hs
		148446 MCM4_HUMAN (5-700): 0: 636: 31.52		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		724713 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		528403 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH8_HUMAN (2-548): 3.84e-18: 94: 11.29
+	Hs
		832810 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH4_HUMAN (1093-1725): 3.21e-17: 90.9: 8.68
+	Hs
		832555 MCM2_HUMAN (8-690): 0: 643: 28.13		MYH14_HUMAN (941-1430): 7.1e-15: 83.1: 16.06
+	Hs
		832489 MCM2_HUMAN (8-690): 0: 643: 28.13		ITSN1_HUMAN (60-424): 6.95e-14: 79.9: 11.52