HitPredict

Interactor 1: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Interactor 2: TIM (Q9UNS1)
Protein timeless homolog (hTIM)
Gene: TIMELESS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 21573113
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 719 Hs			1 1208
+	Hs
		708801 MCM5_HUMAN (6-716): 0: 682: 27.61		TIM_HUMAN (1-1208): 0: 1614: 100.00
+	Hs
		832779 MCM2_HUMAN (8-690): 0: 643: 28.13		TIM_HUMAN (1-1208): 0: 1614: 100.00
+	Mm
		956199 MCM2_MOUSE (8-690): 0: 641: 28.13		TIM_MOUSE (1-1207): 0: 1520: 82.98
+	Sc
		667876 MCM5_YEAST (5-716): 0: 666: 27.77		TOF1_YEAST (25-559): 4.17e-112: 381: 21.50
+	Sc
		675541 MCM4_YEAST (7-703): 0: 658: 29.69		TOF1_YEAST (25-559): 4.17e-112: 381: 21.50
+	Sc
		744784 MCM7_YEAST (2-719): 0: 643: 45.41		TOF1_YEAST (25-559): 4.17e-112: 381: 21.50
+	Sc
		858997 MCM6_YEAST (9-704): 0: 616: 29.69		TOF1_YEAST (25-559): 4.17e-112: 381: 21.50
+	Sp
		772838 MCM2_SCHPO (3-666): 0: 622: 30.42		SWI1_SCHPO (602-822): 5.03e-12: 72.6: 22.69