Interactor 1: ECR (P34021)
Ecdysone receptor (20-hydroxy-ecdysone receptor) (20E receptor) (EcRH) (Ecdysteroid receptor) (Nuclear receptor subfamily 1 group H member 1)
Gene: ECR

Interactor 2: HR38 (P49869)
Probable nuclear hormone receptor HR38 (dHR38) (Nuclear receptor subfamily 4 group A member 4)
Gene: HR38

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 22628309
Identification Methods protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001046 - core promoter sequence-specific DNA binding
GO:0004879 - nuclear receptor activity
and 7 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 878
Dm

1 1073
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024