HitPredict

Interactor 1: ECR (P34021)
Ecdysone receptor (20-hydroxy-ecdysone receptor) (20E receptor) (EcRH) (Ecdysteroid receptor) (Nuclear receptor subfamily 1 group H member 1)
Gene: ECR

Interactor 2: Q9VDE3 (Q9VDE3)
LD08669p (Slimb) (Supernumerary limbs, isoform A) (Supernumerary limbs, isoform C)
Gene: slmb

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 878 Dm			1 510
+	Hs
		370377 ESR1_HUMAN (107-681): 2.93e-121: 381: 21.81		TBL1R_HUMAN (89-362): 8.98e-45: 166: 14.16
+	Hs
		1269548 ESR2_HUMAN (124-682): 1.76e-115: 364: 18.74		TBL1R_HUMAN (89-362): 8.98e-45: 166: 14.16
+	Hs
		740596 PPARG_HUMAN (231-650): 1.2e-103: 332: 26.64		TBL1R_HUMAN (89-362): 8.98e-45: 166: 14.16
+	Hs
		488022 RARA_HUMAN (179-660): 2.25e-102: 327: 25.00		TBL1R_HUMAN (89-362): 8.98e-45: 166: 14.16
+	Hs
		500446 THA_HUMAN (216-617): 1.04e-100: 324: 28.75		TBL1R_HUMAN (89-362): 8.98e-45: 166: 14.16
+	Hs
		377442 GCR_HUMAN (115-665): 1.5e-100: 332: 19.89		WDR86_HUMAN (43-330): 2.28e-42: 156: 16.78
+	Hs
		500505 THB_HUMAN (209-651): 2.02e-100: 322: 27.90		TBL1R_HUMAN (89-362): 8.98e-45: 166: 14.16
+	Hs
		377562 GCR_HUMAN (115-665): 1.5e-100: 332: 19.89		FBXW7_HUMAN (358-510): 1.82e-37: 148: 28.57
+	Xl
		546250 THAA_XENLA (204-655): 3.22e-98: 314: 25.82		TB1RA_XENLA (89-362): 1.52e-44: 165: 14.16
+	Hs
		369932 ESR1_HUMAN (107-681): 2.93e-121: 381: 21.81		WDR5B_HUMAN (90-275): 4.79e-21: 96.1: 17.44
+	Hs
		369305 ESR1_HUMAN (107-681): 2.93e-121: 381: 21.81		WDR5_HUMAN (63-275): 1.56e-20: 94.6: 13.84
+	Hs
		903403 ESR2_HUMAN (124-682): 1.76e-115: 364: 18.74		WDR5_HUMAN (63-275): 1.56e-20: 94.6: 13.84
+	Hs
		1269746 ESR2_HUMAN (124-682): 1.76e-115: 364: 18.74		NLE1_HUMAN (50-235): 1.47e-17: 87.2: 14.36
+	Hs
		740487 PPARG_HUMAN (231-650): 1.2e-103: 332: 26.64		WDR5_HUMAN (63-275): 1.56e-20: 94.6: 13.84
+	Hs
		782513 HNF4A_HUMAN (241-748): 4.46e-104: 332: 20.90		WDR5_HUMAN (63-275): 1.56e-20: 94.6: 13.84
+	Mm
		903664 ERR2_MOUSE (159-653): 1.43e-98: 316: 20.83		WDR5_MOUSE (63-275): 1.56e-20: 94.6: 13.84