HitPredict

Interactor 1: NIC96 (P34077)
Nucleoporin NIC96 (96 kDa nucleoporin-interacting component) (Nuclear pore protein NIC96)
Gene: NIC96

Interactor 2: NU100 (Q02629)
Nucleoporin NUP100/NSP100 (Nuclear pore protein NUP100/NSP100)
Gene: NUP100

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29033133, 18046405, 17418788
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006606 - protein import into nucleus GO:0006913 - nucleocytoplasmic transport GO:0017056 - structural constituent of nuclear pore and 1 others more... GO:0031965 - nuclear membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 839 Sc			1 959
+	Sc
		709322 NIC96_YEAST (1-839): 0: 950: 100.00		NU159_YEAST (236-794): 8.24e-27: 120: 11.19
+	Sc
		709345 NIC96_YEAST (1-839): 0: 950: 100.00		NU116_YEAST (1-815): 1.7e-21: 103: 15.12
+	Sc
		709330 NIC96_YEAST (1-839): 0: 950: 100.00		NU145_YEAST (151-514): 8.4e-21: 100: 20.06
+	Sc
		541865 NIC96_YEAST (1-839): 0: 950: 100.00		NSP1_YEAST (1-496): 6.13e-14: 78.5: 13.58
+	Sc
		709328 NIC96_YEAST (1-839): 0: 950: 100.00		NUP57_YEAST (281-544): 4.23e-13: 74.9: 26.42
+	Sc
		709329 NIC96_YEAST (1-839): 0: 950: 100.00		NUP42_YEAST (413-807): 3.6e-09: 62.3: 11.53
+	Sc
		709342 NIC96_YEAST (1-839): 0: 950: 100.00		NUP49_YEAST (288-527): 6.19e-09: 61.7: 30.52
+	At
		186661 NP93A_ARATH (13-785): 0: 690: 17.70		NU98A_ARATH (1-955): 1.57e-78: 279: 16.86
+	Xl
		1125565 NUP93_XENLA (16-839): 0: 785: 24.57		Q5EWX9_XENLA (110-617): 7.65e-27: 120: 10.00
+	Hs
		727286 NUP93_HUMAN (16-839): 0: 803: 24.51		NU214_HUMAN (80-796): 4.91e-17: 88.9: 10.43
+	Hs
		834630 NUP93_HUMAN (16-839): 0: 803: 24.51		NU153_HUMAN (18-558): 4.59e-17: 88.9: 12.20
+	Tt
		101852 NIC96_CHATD (38-838): 0: 751: 26.97		NSP1_CHATD (119-580): 3.59e-12: 72.3: 14.19
+	Tt
		101851 NIC96_CHATD (38-838): 0: 751: 26.97		NUP49_CHATD (93-347): 9.67e-09: 60.9: 20.39
+	Ce
		136531 Q9BKT9_CAEEL (166-839): 1.73e-172: 519: 19.38		O01576_CAEEL (104-691): 1.47e-13: 76.9: 10.54
+	Ce
		954510 Q9BKT9_CAEEL (166-839): 1.73e-172: 519: 19.38		P91457_CAEEL (10-683): 5.09e-13: 75.7: 10.52
+	Ce
		1308382 Q9BKT9_CAEEL (166-839): 1.73e-172: 519: 19.38		Q9U3B9_CAEEL (7-218): 2.44e-09: 63.4: 16.90