HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)
Gene: PSMB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 277
+	Hs
		1303479 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB7_HUMAN (1-277): 2.34e-107: 314: 100.00
+	Hs
		689 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		690 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		691 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		656297 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656638 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		656760 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Dm
		1359016 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9VUJ1_DROME (10-277): 2.75e-87: 262: 64.82
+	Hs
		656133 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB9_HUMAN (42-227): 9.71e-21: 89.7: 29.41
+	Dm
		1178951 PSMD1_DROME (2-894): 0: 1056: 58.84		Q7K148_DROME (5-251): 4.24e-78: 239: 26.91
+	Dm
		1278636 PSMD1_DROME (2-894): 0: 1056: 58.84		PSA5_DROME (13-242): 1.22e-78: 239: 17.14
+	Sc
		625919 RPN2_YEAST (2-914): 0: 919: 38.04		PSB2_YEAST (11-272): 6.97e-82: 248: 54.92
+	Sc
		689159 RPN2_YEAST (2-914): 0: 919: 38.04		PSA5_YEAST (13-253): 6.07e-77: 236: 20.62
+	Dm
		47613 PSMD1_DROME (2-894): 0: 1056: 58.84		A0AQH0_DROME (42-227): 1.55e-22: 94.4: 29.41
+	Sc
		675399 RPN2_YEAST (2-914): 0: 919: 38.04		PSB5_YEAST (5-246): 1.85e-70: 220: 22.54
+	Sc
		693292 RPN2_YEAST (2-914): 0: 919: 38.04		PSB1_YEAST (43-222): 1.62e-26: 104: 32.04
+	Hs
		656214 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656593 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSB6_HUMAN (41-229): 3.57e-76: 233: 31.58
+	Hs
		656707 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		656112 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSB9_HUMAN (42-227): 9.71e-21: 89.7: 29.41