Interactor 1: VPS35 (P34110)
Vacuolar protein sorting-associated protein 35 (Vacuolar protein-targeting protein 7)
Gene: VPS35

Interactor 2: PEP8 (P40335)
Carboxypeptidase Y-deficient protein 8 (Vacuolar protein sorting-associated protein 26) (Vacuolar protein-targeting protein 4)
Gene: PEP8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 11598206, 9700157, 15965486, 17696874, 37968396, 16554755, 28100638, 17892535, 22940862, 22593205, 16429126
Identification Methods coimmunoprecipitation, affinity chromatography technology, anti bait coimmunoprecipitation, biochemical, pull down, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Vps26~Vps35
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0012505 - endomembrane system
and 5 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 944
Sc

1 379
+ Dm
+ At
+ At
+ Hs
+ Mm
+ At
+ Hs
+ Mm
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024