HitPredict

Interactor 1: HSL1 (P34244)
Probable serine/threonine-protein kinase HSL1 (EC 2.7.11.1)
Gene: HSL1

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16319894
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1518 Sc			1 700
+	Rn
		222476 MRCKB_RAT (72-1121): 1.94e-150: 503: 17.11		MRCKA_RAT (54-661): 2.71e-73: 261: 15.41
+	Hs
		1137917 MRCKB_HUMAN (72-1152): 5.9e-147: 494: 16.82		MRCKA_HUMAN (54-661): 8.72e-70: 250: 14.93
+	Rn
		222472 MRCKA_RAT (62-1141): 3.89e-140: 474: 15.70		MRCKA_RAT (54-661): 2.71e-73: 261: 15.41
+	Hs
		1137871 MRCKA_HUMAN (62-1141): 2.86e-139: 472: 15.52		MRCKA_HUMAN (54-661): 8.72e-70: 250: 14.93
+	Rn
		1186812 MRCKB_RAT (72-1121): 1.94e-150: 503: 17.11		MRCKB_RAT (67-632): 1.56e-38: 156: 13.88
+	Hs
		1035166 ROCK1_HUMAN (72-1105): 1.34e-139: 466: 15.48		ROCK1_HUMAN (141-637): 1.52e-25: 115: 13.87
+	Hs
		1268126 MRCKB_HUMAN (72-1152): 5.9e-147: 494: 16.82		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		254476 ROCK2_HUMAN (79-1103): 1.13e-130: 442: 14.59		ROCK1_HUMAN (141-637): 1.52e-25: 115: 13.87
+	Hs
		724810 ROCK1_HUMAN (72-1105): 1.34e-139: 466: 15.48		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Rn
		92843 ROCK2_RAT (79-1097): 2.13e-131: 444: 14.39		CTRO_RAT (100-632): 5.72e-16: 84.7: 11.34
+	Hs
		724967 MARK4_HUMAN (24-740): 8.62e-136: 439: 21.57		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		725223 MARK4_HUMAN (24-740): 8.62e-136: 439: 21.57		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88
+	Rn
		871291 AAPK1_RAT (62-630): 1.12e-135: 432: 22.94		MYH9_RAT (255-666): 4.36e-18: 91.3: 12.47
+	Hs
		725010 SIK2_HUMAN (72-946): 5.48e-132: 434: 21.95		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		725242 SIK2_HUMAN (72-946): 5.48e-132: 434: 21.95		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88
+	Hs
		1268074 MARK4_HUMAN (24-740): 8.62e-136: 439: 21.57		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		728513 SIK2_HUMAN (72-946): 5.48e-132: 434: 21.95		MYH11_HUMAN (394-666): 8.64e-10: 64.7: 13.41
+	Rn
		102485 AAPK1_RAT (62-630): 1.12e-135: 432: 22.94		G3V6P7_RAT (366-657): 6.94e-09: 61.6: 12.00