HitPredict

Interactor 1: YKA7 (P34258)
Uncharacterized protein B0303.7
Gene: B0303.7

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH2~SH3_1, SH3_1~SH3_1, SH3_1~SH3_2
Common GO terms	GO:0016477 - cell migration
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 493 Ce			1 395
+	Hs
		208989 NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		208958 NCK2_HUMAN (126-351): 3.85e-29: 120: 18.72		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		557594 NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83		NCK1_HUMAN (2-394): 6.74e-80: 252: 37.78
+	Mm
		223015 SRBS1_MOUSE (49-328): 5.08e-19: 92.6: 13.96		NCK2_MOUSE (2-393): 3.3e-84: 263: 38.07
+	Hs
		411817 SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Hs
		1349275 ITSN2_HUMAN (185-437): 5.28e-24: 108: 18.22		ITSN2_HUMAN (8-285): 3.74e-34: 136: 19.61
+	Hs
		1078919 ITSN2_HUMAN (185-437): 5.28e-24: 108: 18.22		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Hs
		557655 NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		1078828 ITSN1_HUMAN (27-493): 1.28e-20: 98: 14.14		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Hs
		557615 NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Hs
		411986 NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83		FYN_HUMAN (6-244): 7.07e-19: 90.2: 12.45
+	Mm
		763403 NCK1_MOUSE (130-350): 3.76e-31: 125: 16.96		FYN_MOUSE (6-244): 6.88e-19: 90.2: 12.45
+	Hs
		924617 SH319_HUMAN (176-413): 5.3e-22: 101: 19.60		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		655386 ITSN1_HUMAN (27-493): 1.28e-20: 98: 14.14		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Ce
		1353618 Q9U2T9_CAEEL (30-493): 7.29e-30: 126: 14.76		Q9U2T9_CAEEL (2-58): 6.33e-11: 66.2: 26.67
+	Ce
		220205 SEM5_CAEEL (255-335): 3.44e-21: 94.2: 25.93		SRC2_CAEEL (6-118): 2.25e-14: 76.4: 15.65
+	Hs
		442869 SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47		HCK_HUMAN (2-186): 3.18e-19: 91.4: 16.13
+	Hs
		412296 SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47		FYN_HUMAN (6-244): 7.07e-19: 90.2: 12.45