HitPredict

Interactor 1: LIN36 (P34427)
Protein lin-36 (Abnormal cell lineage protein 36)
Gene: lin-36

Interactor 2: Q20298 (Q20298)
GRIP domain-containing protein
Gene: CELE_F41H10.4

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	12679813, 10615043, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 962 Ce			1 575
+	Hs
		1192135 HUWE1_HUMAN (501-913): 2.67e-35: 148: 18.49		RBCC1_HUMAN (73-568): 1.24e-26: 117: 16.07
+	Hs
		1192196 HUWE1_HUMAN (501-913): 2.67e-35: 148: 18.49		CP250_HUMAN (2-529): 4.16e-15: 81.3: 10.85
+	Hs
		724896 HUWE1_HUMAN (501-913): 2.67e-35: 148: 18.49		MYH9_HUMAN (220-572): 1.11e-10: 67: 11.36
+	Hs
		876412 AFAD_HUMAN (447-951): 2.44e-15: 83.3: 11.72		MRCKA_HUMAN (50-507): 2.36e-28: 122: 15.23
+	Hs
		876402 AFAD_HUMAN (447-951): 2.44e-15: 83.3: 11.72		GRDN_HUMAN (36-571): 2.52e-18: 91.3: 15.39
+	Hs
		876370 AFAD_HUMAN (447-951): 2.44e-15: 83.3: 11.72		CGNL1_HUMAN (18-564): 8.77e-18: 89.5: 14.65
+	Hs
		725139 ANK2_HUMAN (380-950): 3.86e-12: 73.2: 10.48		MYH10_HUMAN (246-572): 5.08e-11: 68.2: 11.01
+	Hs
		551790 TITIN_HUMAN (379-957): 2.15e-11: 70.6: 9.40		DESP_HUMAN (1-488): 1.32e-11: 69.8: 14.40
+	Hs
		724782 ANK2_HUMAN (380-950): 3.86e-12: 73.2: 10.48		MYH9_HUMAN (220-572): 1.11e-10: 67: 11.36
+	Hs
		724893 MICA3_HUMAN (381-951): 2.41e-09: 63.5: 10.54		MYH9_HUMAN (220-572): 1.11e-10: 67: 11.36
+	Dm
		404245 TITIN_DROME (385-951): 3.99e-09: 63.3: 7.85		MYSA_DROME (10-561): 8.9e-11: 67.1: 11.77