HitPredict

Interactor 1: HNRC2 (B2RXH8)
Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2)
Gene: HNRNPCL2

Interactor 2: SRS12 (Q8WXF0)
Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)
Gene: SRSF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 293 Hs			1 261
+	Hs
		241386 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		241249 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Hs
		201644 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		MSI1H_HUMAN (2-95): 2.87e-22: 96: 26.60
+	Hs
		432996 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		432657 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		1197556 RALYL_HUMAN (2-271): 1.26e-72: 226: 48.10		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		432527 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		1356521 RALY_HUMAN (2-280): 2.93e-66: 210: 40.33		PPIE_HUMAN (10-98): 7.46e-34: 126: 33.71
+	Hs
		432739 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		SRSF7_HUMAN (1-108): 2.53e-09: 58.2: 35.78
+	Mm
		665756 RALY_MOUSE (2-280): 6.45e-73: 228: 38.76		PABP1_MOUSE (2-101): 4.72e-19: 88.3: 17.00
+	Hs
		952174 RALY_HUMAN (2-280): 2.93e-66: 210: 40.33		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		516734 RALY_HUMAN (2-280): 2.93e-66: 210: 40.33		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Hs
		1084447 RALY_HUMAN (2-280): 2.93e-66: 210: 40.33		SRSF7_HUMAN (1-108): 2.53e-09: 58.2: 35.78
+	Hs
		267035 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Hs
		1263482 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		RBMX2_HUMAN (12-261): 2.44e-31: 119: 18.00
+	Hs
		952060 SRS12_HUMAN (12-244): 2.13e-34: 127: 14.52		SRSF3_HUMAN (1-92): 1.68e-23: 95: 32.61
+	Hs
		266958 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		SRS10_HUMAN (1-229): 6.35e-34: 125: 50.00
+	Mm
		925159 TRA2B_MOUSE (25-151): 2.98e-21: 92.7: 23.08		SRSF3_MOUSE (1-92): 1.68e-23: 95: 32.61
+	Hs
		516451 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		PABP1_HUMAN (2-101): 3.98e-19: 88.3: 17.00
+	Mm
		857303 TRA2B_MOUSE (25-151): 2.98e-21: 92.7: 23.08		TIA1_MOUSE (5-100): 2.05e-17: 82.5: 17.71