HitPredict

Interactor 1: ALXA (P34552)
Apoptosis-linked gene 2-interacting protein X 1 (Prion-like-(Q/N-rich) domain-bearing protein 58) (Protein YNK1)
Gene: alx-1

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 882 Ce			1 395
+	Hs
		1260413 PDC6I_HUMAN (1-878): 0: 730: 37.66		ITSN2_HUMAN (8-285): 3.74e-34: 136: 19.61
+	Hs
		1078881 PDC6I_HUMAN (1-878): 0: 730: 37.66		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Hs
		924726 PDC6I_HUMAN (1-878): 0: 730: 37.66		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Mm
		1141174 PDC6I_MOUSE (1-878): 0: 715: 37.32		GRB2_MOUSE (5-175): 1.35e-28: 113: 20.83
+	Hs
		442861 PDC6I_HUMAN (1-878): 0: 730: 37.66		HCK_HUMAN (2-186): 3.18e-19: 91.4: 16.13
+	Hs
		412278 PDC6I_HUMAN (1-878): 0: 730: 37.66		FYN_HUMAN (6-244): 7.07e-19: 90.2: 12.45
+	Hs
		433429 PDC6I_HUMAN (1-878): 0: 730: 37.66		YES_HUMAN (5-108): 6.99e-17: 84.4: 17.93
+	Hs
		523081 PDC6I_HUMAN (1-878): 0: 730: 37.66		SRC_HUMAN (43-217): 1.14e-12: 71.3: 16.95
+	Mm
		403468 PDC6I_MOUSE (1-878): 0: 715: 37.32		SRC_MOUSE (43-180): 9.38e-12: 68.3: 21.58
+	Ce
		712282 ALXA_CAEEL (1-882): 0: 700: 100.00		Q9U2T9_CAEEL (2-58): 6.33e-11: 66.2: 26.67
+	Hs
		1078907 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		ITSN1_HUMAN (5-269): 1.04e-31: 129: 14.46
+	Hs
		924858 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		523149 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		SRC_HUMAN (43-217): 1.14e-12: 71.3: 16.95
+	Hs
		209058 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		NCK2_HUMAN (2-393): 1.95e-85: 266: 37.31
+	Hs
		411694 EP300_HUMAN (638-879): 1.12e-22: 107: 12.25		LCK_HUMAN (176-378): 5.2e-55: 190: 30.05
+	Hs
		924521 EP300_HUMAN (638-879): 1.12e-22: 107: 12.25		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		655342 EP300_HUMAN (638-879): 1.12e-22: 107: 12.25		P85A_HUMAN (270-393): 4.44e-20: 94.5: 19.69
+	Hs
		522942 EP300_HUMAN (638-879): 1.12e-22: 107: 12.25		SRC_HUMAN (43-217): 1.14e-12: 71.3: 16.95
+	Hs
		924592 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		GRB2_HUMAN (5-175): 1.72e-28: 112: 20.37
+	Hs
		433362 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		YES_HUMAN (5-108): 6.99e-17: 84.4: 17.93