HitPredict

Interactor 1: ALXA (P34552)
Apoptosis-linked gene 2-interacting protein X 1 (Prion-like-(Q/N-rich) domain-bearing protein 58) (Protein YNK1)
Gene: alx-1

Interactor 2: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.50	0.589

Property	Details
Experiments	23424658, 18298590, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 882 Ce			1 1085
+	Hs
		1260413 PDC6I_HUMAN (1-878): 0: 730: 37.66		ITSN2_HUMAN (475-1085): 1.13e-26: 120: 14.82
+	Hs
		1078881 PDC6I_HUMAN (1-878): 0: 730: 37.66		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		924726 PDC6I_HUMAN (1-878): 0: 730: 37.66		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		1260427 PDC6I_HUMAN (1-878): 0: 730: 37.66		CD2AP_HUMAN (600-725): 2.26e-11: 70.1: 22.22
+	Ce
		711197 ALXA_CAEEL (1-882): 0: 700: 100.00		YKA7_CAEEL (665-936): 1.1e-19: 95.9: 16.61
+	Mm
		1141174 PDC6I_MOUSE (1-878): 0: 715: 37.32		GRB2_MOUSE (1030-1085): 5.12e-13: 71.3: 33.33
+	Ce
		712280 ALXA_CAEEL (1-882): 0: 700: 100.00		Q95PW9_CAEEL (670-843): 3.79e-09: 62: 26.55
+	Hs
		787971 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Hs
		1126375 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		SH319_HUMAN (722-1084): 1.39e-34: 144: 18.88
+	Hs
		1078907 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		924858 PTN23_HUMAN (4-882): 1.21e-165: 525: 20.34		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		924521 EP300_HUMAN (638-879): 1.12e-22: 107: 12.25		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		209058 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		NCK2_HUMAN (660-960): 3.34e-25: 110: 18.69
+	Hs
		924592 SF3A2_HUMAN (723-879): 1.46e-09: 63.4: 18.75		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33