HitPredict

Interactor 1: HNRC2 (B2RXH8)
Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2)
Gene: HNRNPCL2

Interactor 2: MKRN2 (Q9H000)
E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2)
Gene: MKRN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 416
+	Hs
		241362 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		432912 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		241381 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		432978 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		432680 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		925122 TRA2B_HUMAN (25-151): 2.98e-21: 92.7: 23.08		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1314615 RBM4_HUMAN (17-92): 1e-16: 81.1: 19.74		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1308763 RBM4B_HUMAN (17-114): 1.88e-16: 80.3: 16.33		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1347164 RFOX1_HUMAN (2-162): 1.25e-25: 106: 16.85		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		432803 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		1308806 RBM4B_HUMAN (17-114): 1.88e-16: 80.3: 16.33		ZC3H4_HUMAN (5-55): 8.4e-15: 78.7: 41.18
+	Hs
		1299418 RBM14_HUMAN (17-116): 2.2e-12: 69.2: 20.79		ZC3H4_HUMAN (5-55): 8.4e-15: 78.7: 41.18