HitPredict

Interactor 1: TPPC3 (P34605)
Trafficking protein particle complex subunit 3 homolog
Gene: trpp-3

Interactor 2: Q20100 (Q20100)
Trafficking protein particle complex subunit
Gene: trpp-4

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

Property	Details
Experiments	19123269, 14704431
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Sybindin~TRAPP
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0030008 - TRAPP complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 181 Ce			1 224
+	Hs
		208755 TPPC3_HUMAN (11-180): 1.21e-88: 259: 49.43		TPPC4_HUMAN (5-217): 1.65e-109: 315: 47.89
+	Dm
		1370067 Q9VSY8_DROME (11-180): 9.02e-79: 233: 43.68		Q9VLI9_DROME (5-217): 1.16e-106: 307: 43.66
+	Hs
		1132770 TPC3L_HUMAN (11-174): 2.06e-71: 215: 40.83		TPPC4_HUMAN (5-217): 1.65e-109: 315: 47.89
+	Mm
		222943 TPPC3_MOUSE (11-180): 7.78e-89: 259: 48.28		TPPC1_MOUSE (112-215): 5.5e-42: 140: 22.12
+	Hs
		208759 TPPC3_HUMAN (11-180): 1.21e-88: 259: 49.43		TPPC1_HUMAN (112-215): 6.52e-41: 138: 21.15
+	Sc
		733735 BET3_YEAST (1-180): 3.77e-84: 248: 35.14		BET5_YEAST (112-196): 1.59e-29: 109: 17.65
+	Hs
		1132772 TPC3L_HUMAN (11-174): 2.06e-71: 215: 40.83		TPPC1_HUMAN (112-215): 6.52e-41: 138: 21.15
+	Sc
		733737 BET3_YEAST (1-180): 3.77e-84: 248: 35.14		TRS23_YEAST (136-216): 1.54e-23: 95.5: 34.62