HitPredict

Interactor 1: JIP (P34609)
JNK-interacting protein (JIP) (JNK MAP kinase scaffold protein) (Uncoordinated protein 16)
Gene: unc-16

Interactor 2: KLC (P46822)
Kinesin light chain (KLC)
Gene: klc-2

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.926

The method score is based on:

Property Details
Experiments 19123269, 21307258, 15563606, 21195138, 14704431
Identification Methods two hybrid, affinity chromatography technology, protein complementation assay, two hybrid pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains JIP_LZII~TPR_12
Common GO terms GO:0005737 - cytoplasm
GO:0019894 - kinesin binding
GO:0040011 - locomotion
GO:0048489 - synaptic vesicle transport
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1190
Ce

1 540
+ Dm
+ Mm
+ Mm
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024