HitPredict

Interactor 1: UBXN4 (P34631)
UBX domain-containing protein 4 (Erasin)
Gene: ubxn-4

Interactor 2: TERA2 (P54812)
Transitional endoplasmic reticulum ATPase homolog 2 (EC 3.6.4.6) (Cell division cycle-related protein 48.2) (p97/CDC48 homolog 2)
Gene: cdc-48.2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20977550
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CDC48_2~UBX, CDC48_N~UBX
Common GO terms	GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 469 Ce			1 810
+	Ce
		712421 UBXN4_CAEEL (1-469): 1.07e-137: 405: 100.00		TERA1_CAEEL (1-810): 0: 732: 87.69
+	Hs
		875167 UBXN4_HUMAN (1-469): 1.65e-113: 345: 23.20		TERA_HUMAN (12-788): 0: 727: 78.79
+	Hs
		299344 UBXN7_HUMAN (2-359): 4.68e-84: 269: 16.30		TERA_HUMAN (12-788): 0: 727: 78.79
+	Hs
		875290 ASPC1_HUMAN (51-444): 2.91e-63: 216: 14.22		TERA_HUMAN (12-788): 0: 727: 78.79
+	Dm
		1180101 Q7K4I5_DROME (2-360): 3.84e-60: 206: 12.91		TERA_DROME (12-810): 0: 734: 78.30
+	Sc
		636608 UBX7_YEAST (184-467): 1.42e-61: 208: 18.15		CDC48_YEAST (6-810): 0: 715: 64.89
+	Ce
		873015 UBXN1_CAEEL (64-356): 7.33e-50: 173: 20.81		TERA2_CAEEL (1-791): 0: 746: 100.00
+	Ce
		873005 UBXN1_CAEEL (64-356): 7.33e-50: 173: 20.81		TERA1_CAEEL (1-810): 0: 732: 87.69
+	Hs
		875432 FAF1_HUMAN (168-360): 1.12e-43: 164: 20.21		TERA_HUMAN (12-788): 0: 727: 78.79
+	Mm
		872336 FAF1_MOUSE (168-360): 4.63e-43: 162: 20.73		TERA_MOUSE (12-788): 0: 727: 78.79
+	Mm
		967687 UBXN1_MOUSE (70-359): 2.03e-44: 159: 19.06		TERA_MOUSE (12-788): 0: 727: 78.79
+	Hs
		874846 UBXN1_HUMAN (70-359): 3.63e-42: 153: 18.73		TERA_HUMAN (12-788): 0: 727: 78.79
+	Hs
		875291 UBXN6_HUMAN (176-371): 1.67e-33: 133: 13.57		TERA_HUMAN (12-788): 0: 727: 78.79
+	Hs
		116676 UBXN8_HUMAN (173-361): 1.87e-33: 128: 10.42		TERA_HUMAN (12-788): 0: 727: 78.79
+	Sc
		636664 UBX6_YEAST (145-391): 2.01e-36: 140: 16.05		CDC48_YEAST (6-810): 0: 715: 64.89
+	Sc
		636759 UBX5_YEAST (2-196): 3.96e-34: 135: 13.37		CDC48_YEAST (6-810): 0: 715: 64.89
+	Dm
		1178724 Q7K0S5_DROME (194-363): 1.94e-25: 110: 9.77		TERA_DROME (12-810): 0: 734: 78.30
+	Sc
		636779 UBX3_YEAST (170-361): 2.01e-26: 113: 13.27		CDC48_YEAST (6-810): 0: 715: 64.89
+	Sp
		1014004 YDFB_SCHPO (131-358): 1.78e-31: 122: 16.81		CDC48_SCHPO (1-810): 0: 700: 64.37
+	Hs
		218064 UBXN6_HUMAN (176-371): 1.67e-33: 133: 13.57		PEX1_HUMAN (6-810): 1.63e-121: 398: 25.41