Interactor 1: MCM6 (P34647)
DNA replication licensing factor mcm-6 (EC 3.6.4.12)
Gene: mcm-6

Interactor 2: MCM4 (Q95XQ8)
DNA replication licensing factor mcm-4 (EC 3.6.4.12)
Gene: mcm-4

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 18692475, unassigned701
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM~MCM6_C, MCM6_C~MCM_lid, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 810
Ce

1 823
+ Hs
+ Xl
+ Dm
+ Xl
+ Hs
+ Ce
+ At
+ Dm
+ Hs
+ At
+ Hs
+ Hs
+ At
+ Hs
+ Xl
+ Sp
+ Dm
+ Sp
+ At
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024