HitPredict

Interactor 1: HNRC2 (B2RXH8)
Heterogeneous nuclear ribonucleoprotein C-like 2 (hnRNP C-like-2)
Gene: HNRNPCL2

Interactor 2: RALY (Q9UKM9)
RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)
Gene: RALY

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	32296183, 30021884, 33961781
Identification Methods	two hybrid, proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 306
+	Hs
		241383 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		241314 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		Q53GL6_HUMAN (1-306): 7.94e-142: 403: 97.72
+	Hs
		71142 HNRC2_HUMAN (1-293): 3.5e-94: 281: 100.00		Q53GL6_HUMAN (1-306): 7.94e-142: 403: 97.72
+	Hs
		432988 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		432751 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		Q53GL6_HUMAN (1-306): 7.94e-142: 403: 97.72
+	Hs
		241323 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		71163 HNRC2_HUMAN (1-293): 3.5e-94: 281: 100.00		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		241255 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		241244 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		HNRC1_HUMAN (6-297): 1.05e-98: 293: 43.43
+	Hs
		71043 HNRC1_HUMAN (1-293): 1.3e-98: 293: 96.25		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		71066 HNRC2_HUMAN (1-293): 3.5e-94: 281: 100.00		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432789 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		71024 HNRC2_HUMAN (1-293): 3.5e-94: 281: 100.00		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		432507 HNRPC_HUMAN (1-293): 1.35e-86: 262: 84.64		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38