HitPredict

Interactor 1: TSA1 (P34760)
Peroxiredoxin TSA1 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 1) (cTPx 1) (Protector protein) (PRP) (Thiol-specific antioxidant protein 1) (Thioredoxin peroxidase type Ia) (TPx type Ia) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin TSA1)
Gene: TSA1

Interactor 2: TSA1 (P34760)
Peroxiredoxin TSA1 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 1) (cTPx 1) (Protector protein) (PRP) (Thiol-specific antioxidant protein 1) (Thioredoxin peroxidase type Ia) (TPx type Ia) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin TSA1)
Gene: TSA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 26335398, 30701970, 29557065, 18719252, 19106090, 18725414, 34969852, 19343713, 35234779, 22940862, 22985967
Identification Methods pull down, biochemical, affinity chromatography technology, two hybrid, x-ray crystallography
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 1-cysPrx_C~1-cysPrx_C, 1-cysPrx_C~AhpC-TSA, AhpC-TSA~AhpC-TSA
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006111 - regulation of gluconeogenesis
GO:0006457 - protein folding
and 17 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 196
Sc

1 196
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Sp

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Last updated: 15 Jul 2024