HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	17010992, 21985244, 31980649, 21358815, 14711827, 21832061, 17012257, unassigned2173
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 140
+	Rn
		291982 HSP74_RAT (1-840): 0: 979: 95.83		SYUA_RAT (1-140): 2.23e-57: 176: 95.00
+	Hs
		320823 HS74L_HUMAN (1-840): 0: 959: 63.21		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		742439 HS105_HUMAN (1-840): 0: 938: 62.95		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Hs
		503576 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00
+	Rn
		741578 HSP7C_RAT (564-692): 1.76e-19: 95.5: 16.15		SYUA_RAT (1-140): 2.23e-57: 176: 95.00
+	Hs
		713917 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00