HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 1675
+	Hs
		503904 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		483758 HS71A_HUMAN (571-686): 1.59e-19: 95.5: 23.93		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		713943 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Hs
		564056 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		CLH1_HUMAN (1-1675): 0: 3132: 100.00
+	Sc
		604371 HSP79_YEAST (5-697): 5.63e-139: 429: 38.18		CLH_YEAST (5-1648): 0: 2443: 49.79
+	Sc
		604370 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		CLH_YEAST (5-1648): 0: 2443: 49.79