HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: HSF2 (Q03933)
Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2)
Gene: HSF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	36385105
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 536
+	Hs
		714188 HSP74_HUMAN (1-840): 0: 993: 100.00		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		320844 HS74L_HUMAN (1-840): 0: 959: 63.21		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		961216 HS105_HUMAN (1-840): 0: 938: 62.95		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	At
		612298 HS701_ARATH (2-604): 0: 815: 32.57		HFA1A_ARATH (1-393): 1.42e-93: 296: 20.79
+	Hs
		503937 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		HSF2_HUMAN (1-536): 0: 622: 100.00
+	Sc
		694686 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		SKN7_YEAST (10-471): 1.32e-44: 168: 16.67
+	Sc
		589545 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		SFL1_YEAST (2-145): 5.68e-23: 105: 25.41
+	Mm
		750734 HS71A_MOUSE (571-686): 1e-17: 89.7: 23.08		HSF1_MOUSE (3-467): 1.7e-145: 430: 35.93
+	Hs
		503905 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		961146 Q53FA3_HUMAN (564-691): 3.83e-19: 94.3: 23.26		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	Hs
		713944 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		HSF1_HUMAN (3-466): 1.55e-140: 418: 36.76
+	At
		781120 HS704_ARATH (486-691): 1.05e-17: 89.7: 15.57		HFA1A_ARATH (1-393): 1.42e-93: 296: 20.79
+	Hs
		1120591 Q53FC7_HUMAN (587-690): 3.01e-16: 85.1: 22.86		Q9HAV2_HUMAN (351-466): 1.56e-31: 121: 32.76