HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24366813
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 1128
+	Hs
		1043715 HS105_HUMAN (1-840): 0: 938: 62.95		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		714378 HSP74_HUMAN (1-840): 0: 993: 100.00		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		276146 HSP74_HUMAN (1-840): 0: 993: 100.00		PSD10_HUMAN (988-1128): 3e-43: 159: 16.77
+	Hs
		714414 HSP74_HUMAN (1-840): 0: 993: 100.00		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		714162 HSP74_HUMAN (1-840): 0: 993: 100.00		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		320911 HS74L_HUMAN (1-840): 0: 959: 63.21		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		320835 HS74L_HUMAN (1-840): 0: 959: 63.21		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		504464 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		IASPP_HUMAN (416-1127): 1.13e-53: 204: 21.65
+	Hs
		276135 HS71A_HUMAN (571-686): 1.59e-19: 95.5: 23.93		PSD10_HUMAN (988-1128): 3e-43: 159: 16.77
+	Hs
		714021 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		ANKK1_HUMAN (994-1128): 1.12e-27: 122: 15.22
+	Hs
		504758 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		503777 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		564185 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		564048 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		504362 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		161296 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		225121 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		MYPT2_HUMAN (947-1035): 1.24e-11: 71.4: 33.71