HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: FAF1 (Q9UNN5)
FAS-associated factor 1 (hFAF1) (UBX domain-containing protein 12) (UBX domain-containing protein 3A)
Gene: FAF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	15596450, 28443643, 35704671, 22876279, 23293021
Identification Methods	pull down, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 650
+	Hs
		320930 HS74L_HUMAN (1-840): 0: 959: 63.21		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Hs
		1267785 HS105_HUMAN (1-840): 0: 938: 62.95		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Zm
		8961 A0A1D6FN98_MAIZE (1-832): 0: 872: 37.32		A0A1D6ETD0_MAIZE (500-648): 1.01e-28: 123: 27.81
+	Hs
		504959 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Hs
		564210 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		FAF1_HUMAN (1-650): 0: 840: 100.00
+	Sc
		695795 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		UBX3_YEAST (325-650): 1.72e-53: 191: 20.12
+	Hs
		504548 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		FAF2_HUMAN (320-649): 2.56e-68: 231: 22.29
+	Hs
		504489 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		UBXN4_HUMAN (380-646): 8.5e-35: 140: 17.75
+	Hs
		503939 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		UBXN1_HUMAN (414-649): 9.29e-34: 132: 16.00