Interactor 1: PROF2 (P35080)
Profilin-2 (Profilin II)
Gene: PFN2

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 35271311, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Profilin
Common GO terms GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0016887 - ATP hydrolysis activity
GO:0070062 - extracellular exosome
GO:0098685 - Schaffer collateral - CA1 synapse
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 140
Hs

1 375
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024