HitPredict

Interactor 1: PROF2 (P35080)
Profilin-2 (Profilin II)
Gene: PFN2

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1249
+	Hs
		430197 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		430352 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		243087 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		314847 PROF2_HUMAN (1-140): 2.83e-76: 224: 100.00		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		314830 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		430307 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		FMNL2_HUMAN (10-1000): 6.58e-174: 545: 19.01
+	Hs
		715022 PROF2_HUMAN (1-140): 2.83e-76: 224: 100.00		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		430404 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		237564 PROF2_HUMAN (1-140): 2.83e-76: 224: 100.00		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		237549 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		430356 PROF1_HUMAN (1-140): 4.25e-74: 219: 61.43		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71