HitPredict

Interactor 1: UBL1 (P35127)
Ubiquitin carboxyl-terminal hydrolase YUH1 (UCH) (EC 3.4.19.12) (Ubiquitin thioesterase)
Gene: YUH1

Interactor 2: RUB1 (Q03919)
NEDD8-like protein RUB1 (Related to ubiquitin protein 1) (Ubiquitin-like protein RUB1)
Gene: RUB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12455997
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 236 Sc			1 77
+	Dm
		547969 Q9XZ61_DROME (1-234): 2.16e-88: 265: 20.34		RS27A_DROME (1-76): 1.21e-36: 121: 52.63
+	Hs
		924096 BAP1_HUMAN (5-234): 1.09e-77: 249: 18.37		RS27A_HUMAN (1-76): 3.48e-37: 123: 52.63
+	Sp
		145594 UBLH2_SCHPO (7-234): 1.33e-81: 247: 21.30		UBL1_SCHPO (1-77): 1.91e-33: 111: 59.74
+	Sc
		477613 UBL1_YEAST (1-236): 7.21e-81: 243: 100.00		RL40A_YEAST (1-76): 8.26e-34: 113: 52.63
+	Dm
		547926 CALYP_DROME (1-234): 1.13e-73: 233: 19.52		RS27A_DROME (1-76): 1.21e-36: 121: 52.63
+	Sc
		408320 UBL1_YEAST (1-236): 7.21e-81: 243: 100.00		RS31_YEAST (1-70): 2.28e-30: 105: 50.00
+	Hs
		548102 UCHL3_HUMAN (4-232): 1.9e-77: 234: 29.71		NEDD8_HUMAN (1-76): 1.61e-34: 113: 59.21
+	Hs
		474910 UCHL3_HUMAN (4-232): 1.9e-77: 234: 29.71		UBB_HUMAN (1-76): 2.37e-31: 110: 52.63
+	Hs
		548107 UCHL3_HUMAN (4-232): 1.9e-77: 234: 29.71		Q5U5U6_HUMAN (1-76): 2.37e-31: 110: 52.63
+	Hs
		456536 UCHL1_HUMAN (10-233): 3.6e-68: 211: 24.57		RS27A_HUMAN (1-76): 3.48e-37: 123: 52.63
+	Hs
		456575 UCHL1_HUMAN (10-233): 3.6e-68: 211: 24.57		NEDD8_HUMAN (1-76): 1.61e-34: 113: 59.21
+	Hs
		456474 UCHL1_HUMAN (10-233): 3.6e-68: 211: 24.57		UBB_HUMAN (1-76): 2.37e-31: 110: 52.63
+	Sc
		477215 UBL1_YEAST (1-236): 7.21e-81: 243: 100.00		UBI4P_YEAST (1-76): 1.13e-16: 73.9: 52.63
+	Sp
		145591 UBLH1_SCHPO (8-231): 2.47e-54: 175: 24.03		UBL1_SCHPO (1-77): 1.91e-33: 111: 59.74