HitPredict

Interactor 1: UBE2N (P35128)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme N) (Protein bendless) (Ubiquitin carrier protein N) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase D3) (Ubiquitin-protein ligase N)
Gene: ben

Interactor 2: Q8IQ53 (Q8IQ53)
GEO11416p1 (MIP16420p) (Ubiquitin-conjugating enzyme variant 1A, isoform B)
Gene: Uev1A

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.852

Property	Details
Experiments	19141674, 29518634, 37061542
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~UQ_con
Common GO terms	GO:0005634 - nucleus GO:0006301 - postreplication repair GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 151 Dm			1 103
+	Zm
		74428 B4FCQ9_MAIZE (4-149): 6.25e-81: 236: 46.58		B4FCQ9_MAIZE (2-103): 5.48e-50: 156: 24.51
+	Hs
		1377464 UB2D4_HUMAN (4-149): 1.03e-80: 236: 48.63		UB2D4_HUMAN (2-103): 2.63e-49: 154: 22.55
+	Zm
		79635 B6SZE0_MAIZE (4-149): 1.09e-80: 236: 47.26		B6SZE0_MAIZE (2-103): 3.85e-49: 154: 24.51
+	Hs
		895960 UB2D4_HUMAN (4-149): 1.03e-80: 236: 48.63		UB2D3_HUMAN (2-103): 3.13e-49: 154: 21.57
+	Zm
		41174 A0A1D6NGW9_MAIZE (4-145): 5.09e-78: 232: 45.78		A0A1D6NGW9_MAIZE (2-103): 1.81e-49: 157: 23.53
+	Hs
		849299 UB2D1_HUMAN (4-149): 2.65e-80: 235: 47.26		UB2D3_HUMAN (2-103): 3.13e-49: 154: 21.57
+	Hs
		849296 UB2D1_HUMAN (4-149): 2.65e-80: 235: 47.26		UB2D1_HUMAN (2-103): 1.02e-48: 153: 21.57
+	Hs
		895770 UB2D2_HUMAN (4-149): 7.44e-80: 234: 48.63		UB2D3_HUMAN (2-103): 3.13e-49: 154: 21.57
+	Hs
		919702 UB2D2_HUMAN (4-149): 7.44e-80: 234: 48.63		UB2D2_HUMAN (2-103): 2.93e-49: 154: 21.57
+	Sc
		549783 UBC4_YEAST (1-149): 1.23e-79: 233: 48.32		UBC5_YEAST (2-103): 3.49e-49: 154: 22.55
+	Hs
		895766 UB2D3_HUMAN (4-149): 7.95e-79: 231: 47.95		UB2D3_HUMAN (2-103): 3.13e-49: 154: 21.57
+	Sc
		549782 UBC4_YEAST (1-149): 1.23e-79: 233: 48.32		UBC4_YEAST (2-103): 7.16e-48: 151: 23.53
+	Zm
		8399 A0A1D6ENM7_MAIZE (4-149): 6.64e-80: 235: 46.58		A0A1D6LKH6_MAIZE (2-103): 4.16e-45: 145: 22.55
+	Dm
		1368860 Q9VJS5_DROME (1-151): 1.45e-77: 228: 80.80		Q9VRL1_DROME (1-103): 3.05e-45: 144: 100.00
+	Dm
		1214478 Q9VJS5_DROME (1-151): 1.45e-77: 228: 80.80		Q8IQ53_DROME (1-103): 9.6e-44: 139: 100.00
+	Ce
		220073 UBC13_CAEEL (4-148): 1.04e-77: 228: 81.38		UB2V1_CAEEL (1-103): 1.87e-42: 137: 57.69