Interactor 1: UBC2 (P35129)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Lethal protein 70) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: let-70

Interactor 2: Q9XUS3 (Q9XUS3)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31)
Gene: pdr-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 16204351
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IBR~UQ_con, UQ_con~zf-RING_14
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 147
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1 386
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024