HitPredict

Interactor 1: TOR1 (P35169)
Serine/threonine-protein kinase TOR1 (EC 2.7.11.1) (Dominant rapamycin resistance protein 1) (Phosphatidylinositol kinase homolog TOR1) (Target of rapamycin kinase 1)
Gene: TOR1

Interactor 2: RAGAB (Q00582)
GTP-binding protein GTR1 (EC 3.6.5.-)
Gene: GTR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	29698392, 33566094, 38127619
Identification Methods	affinity chromatography technology, protein complementation assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0010507 - negative regulation of autophagy
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2470 Sc			1 310
+	Sc
		715223 TOR1_YEAST (1-2470): 0: 1922: 100.00		RAGCD_YEAST (2-299): 3.73e-98: 294: 22.40
+	Sc
		696527 TOR2_YEAST (32-2470): 0: 1818: 67.45		RAGAB_YEAST (1-310): 1.12e-131: 378: 100.00
+	Hs
		787573 MTOR_HUMAN (72-2470): 0: 1605: 38.29		RRAGC_HUMAN (4-310): 3.09e-128: 372: 21.38
+	Hs
		787576 MTOR_HUMAN (72-2470): 0: 1605: 38.29		RRAGD_HUMAN (2-310): 1.29e-127: 371: 20.94
+	Hs
		787501 MTOR_HUMAN (72-2470): 0: 1605: 38.29		RRAGB_HUMAN (2-310): 5.54e-127: 369: 47.06
+	Ce
		1095008 TOR_CAEEL (37-2470): 0: 1184: 26.36		Q22743_CAEEL (4-310): 5.66e-124: 359: 46.54
+	Ce
		108071 TOR_CAEEL (37-2470): 0: 1184: 26.36		G5EGB3_CAEEL (4-300): 6.11e-102: 303: 17.33