HitPredict

Interactor 1: SGS1 (P35187)
ATP-dependent helicase SGS1 (EC 5.6.2.4) (DNA 3'-5' helicase Sgs1) (Helicase TPS1)
Gene: SGS1

Interactor 2: SMT3 (Q12306)
Ubiquitin-like protein SMT3
Gene: SMT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	27373152, 25588990, 19158389, 17081974
Identification Methods	two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, covalent binding

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1447 Sc			1 101
+	Hs
		867556 BLM_HUMAN (339-1436): 1.51e-135: 455: 23.33		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		867564 BLM_HUMAN (339-1436): 1.51e-135: 455: 23.33		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		133955 DDX3X_HUMAN (493-1036): 5e-119: 389: 15.39		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Rn
		89015 D4ADE8_RAT (493-1036): 1.8e-118: 388: 15.56		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96
+	Hs
		902579 WRN_HUMAN (377-1363): 1.22e-111: 387: 23.75		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		902699 DDX17_HUMAN (593-1036): 2.17e-117: 387: 17.43		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Hs
		571381 DDX5_HUMAN (566-1036): 3.79e-117: 382: 16.08		SUMO2_HUMAN (9-98): 2.32e-36: 120: 42.86
+	Rn
		1140372 Q6AYI1_RAT (564-1036): 3.94e-117: 382: 16.22		SUMO3_RAT (9-98): 1.04e-35: 119: 43.96
+	Hs
		928094 WRN_HUMAN (377-1363): 1.22e-111: 387: 23.75		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44
+	Hs
		928122 DDX46_HUMAN (391-1323): 2.54e-108: 371: 12.19		SUMO1_HUMAN (1-98): 2.09e-33: 112: 44.44