HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: SOX6 (P35712)
Transcription factor SOX-6
Gene: SOX6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	17412698
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Arm~HMG_box
Common GO terms	GO:0002062 - chondrocyte differentiation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 828
+	Mm
		776233 CTNB1_MOUSE (1-781): 0: 624: 99.87		SOX6_MOUSE (1-828): 0: 619: 96.74
+	Dm
		578667 ARM_DROME (1-780): 9.15e-160: 486: 64.49		PANG2_DROME (144-827): 9.38e-107: 356: 15.27
+	Mm
		970158 CTNB1_MOUSE (1-781): 0: 624: 99.87		TF7L2_MOUSE (326-711): 8.29e-43: 164: 12.92
+	Hs
		717411 CTNB1_HUMAN (1-781): 0: 626: 100.00		LEF1_HUMAN (384-715): 3e-41: 158: 16.72
+	Mm
		653458 CTNB1_MOUSE (1-781): 0: 624: 99.87		LEF1_MOUSE (384-715): 2.16e-41: 158: 17.61
+	Hs
		717031 CTNB1_HUMAN (1-781): 0: 626: 100.00		SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45
+	Xl
		640752 CTNB1_XENLA (1-781): 0: 615: 97.44		T7L1A_XENLA (406-825): 1.44e-41: 162: 13.21
+	Hs
		717368 CTNB1_HUMAN (1-781): 0: 626: 100.00		TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07
+	Hs
		717362 CTNB1_HUMAN (1-781): 0: 626: 100.00		TF7L1_HUMAN (415-783): 1.27e-35: 145: 12.93
+	Hs
		716868 CTNB1_HUMAN (1-781): 0: 626: 100.00		SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02
+	Mm
		818698 CTNB1_MOUSE (1-781): 0: 624: 99.87		SOX2_MOUSE (582-707): 1.37e-36: 142: 38.10
+	Mm
		970176 CTNB1_MOUSE (1-781): 0: 624: 99.87		TF7L1_MOUSE (415-826): 1.01e-34: 142: 12.09
+	Hs
		133758 CTNB1_HUMAN (1-781): 0: 626: 100.00		SOX1_HUMAN (576-694): 8.48e-35: 139: 38.66
+	Hs
		716923 CTNB1_HUMAN (1-781): 0: 626: 100.00		SOX10_HUMAN (523-827): 2.86e-32: 133: 21.29
+	Mm
		970139 CTNB1_MOUSE (1-781): 0: 624: 99.87		SOX17_MOUSE (555-823): 8.79e-31: 128: 26.55
+	Hs
		717348 CTNB1_HUMAN (1-781): 0: 626: 100.00		SOX17_HUMAN (557-815): 4.34e-30: 125: 25.94
+	Hs
		542421 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		CIC_HUMAN (323-827): 1.48e-39: 161: 15.33
+	Hs
		542475 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		LEF1_HUMAN (384-715): 3e-41: 158: 16.72
+	Dm
		578629 ARM_DROME (1-780): 9.15e-160: 486: 64.49		PANG1_DROME (419-827): 3.69e-37: 151: 13.39
+	Hs
		542455 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		TF7L2_HUMAN (327-801): 6.75e-37: 149: 12.07