HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

The method score is based on:

Property	Details
Experiments	27684187, 22519731, 11734550, 12377780, 22662192
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion and 10 others more... GO:0005938 - cell cortex GO:0008543 - fibroblast growth factor receptor signaling pathway GO:0016323 - basolateral plasma membrane GO:0016328 - lateral plasma membrane GO:0019901 - protein kinase binding GO:0019903 - protein phosphatase binding GO:0043410 - positive regulation of MAPK cascade GO:0045296 - cadherin binding GO:0070062 - extracellular exosome GO:1990138 - neuron projection extension
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	781
Hs

1	1657

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024