HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 23539445, 34732716, 23667531
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~HMG_box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001649 - osteoblast differentiation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
and 7 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 781
Hs

1 317
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024