HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 25897075, 26496610, 27684187, 17510365
Identification Methods enzymatic study, affinity chromatography technology, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005102 - signaling receptor binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
and 5 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 781
Hs

1 483
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Mm
+ Hs
+ Dm
+ Hs
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+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024