Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 21743491, 27902311, 29045831, 11251183, 26359353, 27684187, 30181396, 11193155, 30923315, 29789528, 31286874, 33431799, 35968358, 19576224, 25897075, 29568061, 16365045, 30711629, 10330181, 34352208 and 18 others

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Identification Methods affinity chromatography technology, enzymatic study, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001837 - epithelial to mesenchymal transition
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005813 - centrosome
and 16 others

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Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 781
Hs

1 420
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Dm
+ Hs
+ Hs
+ Hs
+ At
+ At

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Last updated: 15 Jul 2024